Management of carcinoma of unknown primary site (CUP), any changes?
نویسندگان
چکیده
منابع مشابه
Carcinoma of unknown primary site (CUP): Outcomes in patients with a colorectal molecular profile treated with site-specific chemotherapy.
3563 Background: Molecular tumor profile assays (MTP) may predict the primary site of origin in CUP, but the impact of site-specific therapy on outcomes is undefined. Accurate identification of CUP patients (pts) with a colorectal site of origin would be expected to improve treatment results by directing the use of colorectal cancer regimens rather than empiric CUP regimens. METHODS We identi...
متن کاملGranulocyte Colony-Stimulating Factor-Producing Carcinoma of Unknown Primary Site
Granulocyte colony-stimulating factor (G-CSF)-producing nonhematopoietic malignancies have been reported in various organs and are associated with a poor clinical outcome. Moreover, carcinoma of unknown primary site (CUP) is an uncommon malignancy that occurs in about 2-6% of cancer patients. CUP also has a poor prognosis due to its missing profile. Since both G-CSF-producing carcinoma and CUP ...
متن کاملManagement of patients with cancer of unknown primary site.
Cancer of unknown primary site represents approximately 3% to 5% of all new cancer diagnoses. Adenocarcinomas account for 60% of all unknown primary cancers and poorly differentiated carcinomas or adenocarcinomas, for 30%. Historically, the prognosis for most patients with unknown primary tumors has been poor, with survival often less than 6 months from diagnosis. Recent advances in diagnostic ...
متن کاملCancer of unknown primary site.
Copyright © 2014 Massachusetts Medical Society Cancer of unknown primary site is a heterogeneous group of cancers for which the anatomical site of origin remains occult after detailed investigations.1,2 The emergence of sophisticated imaging, immunohistochemical testing, and molecular-profiling tools has influenced our approach to unknown primary cancer, although it has also increased the ambig...
متن کاملAdenocarcinoma of Unknown Primary Site
BACKGROUND Metastatic cancer of unknown primary site occupies 0.5-10% of all diagnosed cancer patients and includes various tumors with diverse responses to systemic chemotherapy. Adenocarcinoma of unknown primary site (ACUPS), the most common subtype, has no standard treatment, rarely responds to conventional treatment and has a poor survival rate. METHODS The retrospective study was perform...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2001
ISSN: 0923-7534
DOI: 10.1023/a:1011192414615